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对３０例缓解期哮喘患儿行蒸馏水激发试验，求出最高呼气流速（ＰＥＦＲ）下降２０％所需的蒸馏水量（ＰＤ２０ＰＥＦＲ）。结果表明事先吸入速尿，对激发试验有明显保护作用，ＰＤ２０ＰＥＦＲ从原来的８．１０±４．２３ｍｌ明显增到１６．４０±５．７２ｍｌ（Ｐ＜０．０１），而吸入对照液，则无差异。实验还表明不同的给药途径，也有明显差异。吸入速尿后ＰＤ２０ＰＥＦＲ较吸入前明显增加（Ｐ＜０．０１），而口服速尿则无明显差异，提示吸入速尿可用于哮喘的治疗。
Distilled water challenge tests were performed on 30 children with remission asthma to determine the amount of distilled water (PD20PEFR) required to reduce the maximum expiratory flow (PEFR) by 20%. The results showed that prior inhalation of furosemide had a significant protective effect on the challenge test, PD20PEFR significantly increased from 8.10 ± 4.23ml to 16.40 ± 5.72ml (P <0.01) No difference. Experiments also show that different routes of administration, there are significant differences. PD20PEFR increased significantly (P <0.01) before inhalation of furosemide, while oral furosemide showed no significant difference, suggesting that inhaled furosemide can be used for the treatment of asthma.