Role of gut microbiome in regulating the effectiveness of metformin in reducing colorectal cancer in

• 作 者: Qi-You Huang Fei Yao Chuan-Ren
• 机 构: InstituteofInfection,DepartmentofGastroenterology
• 出 处: 世界临床病例杂志
• 发表日期: 2020年24期
• 关键词: METFORMIN Colorectal cancer Gut microbiota Type 2 diabetes mellitus
• 基金项目: Supported by National NaturalScience Foundation of China, No.81573239.

The prevalence of colorectal cancer (CRC) and type 2 diabetes mellitus (T2DM) isincreasing globally. It is rarely noticed that the incidence of CRC is higher inpatients with T2DM. What needs to be mentioned is that metformin, a commonlyused clinical drug