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采用比色法对５０例耳鼻咽喉恶性肿瘤病人血清唾液酸（ＳＡ）含量进行测定。结果表明，耳鼻咽喉恶性肿瘤病人血清ＳＡ含量较正常对照组和良性疾病组增高，差异有极显著性（Ｐ＜０．０１）。以大于正常对照组血清ＳＡ含量的为阳性，则耳鼻咽喉恶性肿瘤组的阳性率为７２％，良性疾病组阳性率为１６％，差异有极显著性（Ｐ＜０．０１）。各种耳鼻咽喉恶性肿瘤病人之间血清ＳＡ含量差异无显著性（Ｐ＞０．０５）。提示血清ＳＡ含量测定是耳鼻咽喉恶性肿瘤诊断中的一项有价值的辅助指标。
50 patients with otolaryngological malignancies serum sialic acid (SA) content was measured by colorimetric method. The results showed that the content of SA in the serum of patients with otolaryngopharyngeal malignant tumor was higher than that of normal control group and benign disease group (P <0.01). The positive rate of serum SA was higher than that of the normal control group, and the positive rate was 72% in the group of otolaryngolaryngosis and 16% in the benign group, the difference was significant (P <0.01). There was no significant difference in serum SA levels among various otolaryngological malignancies (P> 0.05). Tip serum SA content determination of otolaryngology is a valuable auxiliary diagnosis.