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目的探讨静脉滴注抗生素联合中药保留灌肠对试管婴儿助孕失败合并子宫内膜炎患者的治疗作用。方法将86例IVF周期中1次新鲜胚胎移植失败患者,分为两组。其中,对照组30例,宫腔镜提示正常宫腔;试验组56例,宫腔镜提示子宫内膜炎。对照组不予治疗,直接行冷冻胚胎移植。试验组分为单纯抗生素治疗组(A组)25例,抗生素联合中药保留灌肠组(B组)31例,试验两组给予治疗后行冷冻胚胎移植,比较各组临床妊娠率及胚胎种植率。结果给予冷冻胚胎移植后试验B组的临床妊娠率及胚胎种植率均高于对照组及试验A组,差异有统计学意义(P<0.0 5)。结论抗生素联合中药保留灌肠治疗子宫内膜炎可提高助孕失败后冷冻胚胎移植的临床妊娠率及胚胎种植率。
Objective To investigate the therapeutic effect of intravenous infusion of antibiotics combined with traditional Chinese medicine retention enema on IVF patients with unsuccessive IVF pregnancy. Methods A total of 86 patients with failed fresh embryo transfer during the IVF cycle were divided into two groups. Among them, the control group of 30 cases, hysteroscopy prompted the normal uterine cavity; 56 cases of experimental group, hysteroscopy prompted endometritis. Control group without treatment, direct frozen embryo transfer. The experimental group consisted of 25 cases in the group of antibiotics alone (group A) and 31 in the group of reserving enema (group B) of antibiotics. The two groups were treated with frozen embryo transfer. The clinical pregnancy rate and embryo implantation rate were compared between the two groups. Results The clinical pregnancy rate and embryo implantation rate in experimental group B after freezing embryo transfer were all higher than those in control group and experimental group A, with significant difference (P <0.05). Conclusion Antibiotics combined with traditional Chinese medicine retention enema in the treatment of endometritis can improve the clinical pregnancy rate and embryo implantation rate of frozen embryo transfer failed.