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作者观察了庆大霉素用药方法对肾脏的影响。将庆大霉素4mg／（kg.d）．均分两次，据肌肉注射时间不同分甲（bh），乙（8h）、丙（1uh）三个观察组，通过治疗前及停药后第二天血、尿微球蛋白、血尿素氮、肌酐的测定来评估肾功能。结果表明，甲组病人停药后第二天，尿微球蛋白明显高于用药前（P＜0．01），在正常剂量下，庆大霉素用药时间过短时，仍可损伤肾功能，提出用药间歇时间不少于8h。
The authors observed the effects of gentamicin on the kidneys. Gentamicin 4 mg / (kg.d). According to the intramuscular injection time different points A (bh), B (8h), C (1uh) three observation group, before and after treatment by the second day of blood, urine microglobulin, blood urea nitrogen The creatinine was measured to assess renal function. The results showed that the urinary microglobulin in group A patients was significantly higher than that before treatment (P <0.01) on the second day after drug withdrawal, and at normal dose, gentamicin could still damage renal function when the medication time was too short , Proposed intermittent medication time of not less than 8h.