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涎腺恶性淋巴上皮病损(MLEL)是涎腺罕见的恶性肿瘤之一,具有明显的种族特性,好发于南部中国人。本文对12例MLEL(其中10例有随访资料)进行Keratin,S-100,GFAP,CEA免疫组化染色。结果发现Keratin免疫组化染色反应强者预后好,染色反应弱者预后差。以上四种抗体免疫组化染色结果尚提示MLEL的癌细胞具有与正常腺上皮细胞、肌上皮细胞及鳞状上皮细胞相似的抗原特性,提示该瘤来自涎腺导管上皮,常有鳞状上皮化生
Salivary gland malignant lymphoepithelial lesions (MLEL) is one of the rare malignant tumors of the salivary gland, has obvious ethnic characteristics, occurs in southern Chinese. In this paper, 12 cases of MLEL (including 10 cases with follow-up data) Keratin, S-100, GFAP, CEA immunohistochemical staining. The results showed that Keratin immunohistochemical staining strong prognosis, poor staining reaction poor prognosis. Immunohistochemical staining results of the above four antibodies still suggest MLEL cancer cells with normal glandular epithelial cells, myoepithelial cells and squamous epithelial cells similar antigenic characteristics, suggesting that the tumor from the salivary gland duct epithelium, often squamous epithelial Health