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目的观察一次运动训练对运动员血清IL-2、sIL-2R的影响,寻找运动后机体免疫机能变化规律,从而有效预防运动性免疫抑制。方法以进行无氧训练的武术运动员为研究对象,以血清IL-2、sIL-2R来反映机体免疫机能,观察训练前后不同时相IL-2、sIL-2R的变化。结果适宜的无氧训练后即刻可以使血清IL-2含量在运动后即刻较运动前显著升高,在恢复2h、15h与运动后即刻相比,血清IL-2含量又显著降低;血清sIL-2R在运动后即刻较运动前显著升高。结论适量无氧运动训练后一段时间细胞免疫功能提高,但很快可以恢复,可能是sIL-2R可低亲和力与IL-2结合,减少IL-2与IL-2R结合,导致细胞免疫机能不至于持续保持过高水平,长期过量sIL-2R升高提示机体细胞免疫机能受到抑制,应及时调整训练负荷来减轻运动性免疫抑制的发生。
Objective To observe the effect of exercise training on serum IL-2 and sIL-2R in athletes and find out the regularity of immune function after exercising, so as to effectively prevent exercise-induced immunosuppression. Methods Anaerobic training martial arts athletes as the research object, serum IL-2, sIL-2R to reflect the body's immune function, observe the changes of IL-2, sIL-2R at different time before and after training. Results After anaerobic training, serum IL-2 level immediately after exercise was significantly higher than that before exercise, and the level of IL-2 in serum was significantly decreased at 2h and 15h after recovery. Serum sIL- 2R significantly increased immediately after exercise than before exercise. CONCLUSIONS: After a certain amount of anaerobic exercise training, the cellular immunity function is improved, but it can be recovered quickly. It may be that sIL-2R binds to IL-2 with low affinity and reduces the binding of IL-2 and IL-2R, Sustained high levels of long-term excessive sIL-2R elevation prompted the body's cellular immune function was inhibited, timely training load should be adjusted to reduce the occurrence of exercise-induced immune suppression.