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溶组织内阿米巴有许多特征,例如含有染色体外编码核糖体RNA和溶血素的环状DNA等。作者在分离鉴定编码组蛋白H_3的cDNA基础上,已对组蛋白H_4基因序列及结构进行研究。从C-末端对应序列及组蛋白H_4DNA结合部构建一段变性的寡聚核苷酸
Entamoeba histolytica has many features, such as circular DNA containing extrachromosomal RNA and hemolysin. Based on the isolation and identification of cDNA encoding histone H_3, the sequence and structure of histone H_4 gene have been studied. Construction of a denatured oligonucleotide from the C-terminal counterpart and the histone H_4 DNA binding site