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目的:评估家庭无创正压通气(HNPPV)联合呼吸操对慢性阻塞性肺疾病(COPD)的疗效。方法:80例COPD分为呼吸操+HNPPV组20例和呼吸操组60例。结果:治疗1 a后治疗组PaO2、PaCO2、肺功能、6MW D、呼吸困难分级、辅助呼吸肌评分、年住院次数均优于对照组,具有统计学意义(P均<0.05)。结论:HNPPV联合呼吸操治疗COPD疗效较为肯定。
PURPOSE: To evaluate the efficacy of home-based noninvasive positive pressure ventilation (HNPPV) combined with breathing exercises in patients with chronic obstructive pulmonary disease (COPD). Methods: Eighty COPD patients were divided into respiratory operation + HNPPV group (n = 20) and respiratory operation group (n = 60). Results: PaO2, PaCO2, pulmonary function, 6MW D, dyspnea classification, assisted breathing muscle score and hospitalization in the treatment group were better than those in the control group after 1 year of treatment (P <0.05). Conclusion: The effect of HNPPV combined with respiratory operation in treating COPD is relatively positive.