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白细胞介素-2-毒素是一类新型免疫抑制剂,它能特异性杀灭活化的T淋巴细胞c它的研制成功始于八十年代末,近几年它已被用于各学科领域的动物实验研究。现已证明,它对实验性葡萄膜视网膜炎和角膜移植排斥反应等有显著的治疗作用。本文综述了这类新型免疫抑制剂的毒素种类、载体的性质、生物学活性及其在眼科的研究等方面的资料。
IL-2 is a new class of immunosuppressive agents that specifically kill activated T lymphocytes. Its success began in the late 1980s and in recent years it has been used in various disciplines Animal Experimental Research. It has been demonstrated that it has a significant therapeutic effect on experimental uveitis and keratoplasty rejection. This review summarizes the types of toxins, the nature of their carriers, their biological activity and their usefulness in the research of ophthalmology for these novel immunosuppressive agents.