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本文报告输注新鲜血小板治疗32例重型和危重型流行性出血热,并以22例相同型别流行性出血热作比较。结果显示,治疗组较对照组少尿持续时间平均缩短2.034天(p<0.05)。颅内出血和肺出血发生率明显减少(p<0.05),病死率明显降低(p<0.05),认为早期使用新鲜血小板可起到预防出血作用。对出血症状明显并伴血小板数量和功能明显降低者,更应积极尽早输注血小板,以避免发生大出血。
This article reports the treatment of 32 cases of severe and critically severe epidemic hemorrhagic fever with fresh platelet transfusion, and compared 22 cases of the same type of epidemic hemorrhagic fever. The results showed that the duration of oliguria in treatment group was 2.034 days shorter than that in control group (p <0.05). The incidence of intracranial hemorrhage and pulmonary hemorrhage was significantly reduced (p <0.05), and mortality was significantly lower (p <0.05), suggesting that early use of fresh platelets may prevent bleeding. On the obvious symptoms of bleeding and with significant reduction in the number and function of platelets, but also should be as soon as possible infusion of platelets in order to avoid bleeding.