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目的:对九江地区冬春季急性下呼吸道感染(ALRI)的住院患儿进行呼吸道病毒感染监测,探讨其流行规律。方法:选择2008~2012年冬春季在该院呼吸内科住院的ALRI患儿,取入院当天并病程第5天抽静脉血进行呼吸道病毒IgM监测,包括呼吸道合胞病毒(RSV)、腺病毒(ADV)、流感病毒(IV)、副流感病毒(PIV),并对检查阳性标本的病例进行统计学分析。结果:通过对4年冬春季918例标本监测,呼吸道病毒阳性216例,占23.5%(216/918);呼吸道合胞病毒178例,占阳性标准比例82.4%(178/216);腺病毒8例,占阳性标本3.7%(8/216);流感病毒13例,占阳性标本6.0%(13/216);副流感病毒17例,占阳性标本7.8%(17/216)。RSV的发病高峰在12月~第2年1、2月份,RSV感染多见1岁以下儿童,6个月以下儿童为发病高峰。多见于支气管肺炎和毛细支气管炎患儿,男女发病比例为2.08∶1,且近4年流行趋势大致相同。结论:九江地区引起ALRI的主要病原体为RSV,IV和PIV较低,ADV呈散发性。
Objective: To investigate the prevalence of respiratory virus infection in hospitalized children with acute lower respiratory tract infection (ALRI) in winter and spring in Jiujiang area. Methods: ALRI children hospitalized in the Department of Respiratory Medicine in the winter and spring of 2008 ~ 2012 were enrolled in this study. On the fifth day after admission, venous blood was collected for respiratory viral IgM monitoring, including respiratory syncytial virus (RSV), adenovirus ), Influenza virus (IV), parainfluenza virus (PIV), and the positive samples were examined for statistical analysis. Results: 216 cases (23.5%) had respiratory syncytial virus (216/918), 178 cases of respiratory syncytial virus (82.4%) (178/216), and 918 cases of adenovirus Cases accounted for 3.7% (8/216) of positive samples; 13 cases of influenza viruses accounted for 6.0% (13/216) of positive samples; 17 cases of parainfluenza virus, accounting for 7.8% (17/216) of positive samples. The peak incidence of RSV in December ~ the first two months of January and February, RSV infection more common in children under the age of 1, 6 months of age the peak incidence. More common in children with bronchial pneumonia and bronchiolitis, the incidence of male to female ratio of 2.08: 1, and the nearly 4-year trend is about the same. Conclusion: The main pathogens causing ALRI in Jiujiang are RSV, low IV and PIV, and ADV are sporadic.