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盐酸氯丙嗪的理化性质决定了其口服片剂应包有糖衣或薄膜衣。而近年来国外许多报道指出,糖衣层的物理不稳定性是导致药物释放缓慢的主要原因之一。El-Fattah SA 等(1984)按照美国药典
The physicochemical properties of chlorpromazine hydrochloride determine its oral tablets should be covered with sugar or film coat. In recent years, many foreign reports pointed out that the physical instability of the coating layer is one of the main reasons for the slow release of drugs. El-Fattah SA et al. (1984) according to U.S. Pharmacopeia