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目的检测子痫患者血浆凝血因子及D二聚体指标,了解子痫患者凝血及纤溶功能状态,预测母儿预后。方法收集我院2015年1月至12月分娩的80例孕妇分为两组:正常孕妇(50例)和子痫(30)例。在STAR全自动血凝仪上检测PT、Fbg、aPTT和D二聚体。结果子痫患者PT、aPTT低于正常孕妇组,Fbg和D二聚体高于正常孕妇组,P<0.05。结论子痫患者常伴有凝血和纤溶功能的异常,分娩前孕妇进行凝血功能和血浆D二聚体水平联合检测,有利于监测孕妇凝血及纤溶功能的改变,预测围产期特殊生理状态引起的病理性异常,为早期发现和早期预防子痫具有重要的临床价值。
Objective To detect the plasma coagulation factors and D-dimer in patients with eclampsia to understand the coagulation and fibrinolytic function in patients with eclampsia and predict the prognosis of maternal and infant. Methods Eighty pregnant women who delivered in our hospital from January 2015 to December 2015 were divided into two groups: normal pregnant women (50 cases) and eclampsia (30 cases). PT, Fbg, aPTT and D dimers were detected on a STAR automated coagulometer. Results The levels of PT and aPTT in patients with eclampsia were lower than those in normal pregnant women, and those in Fbg and D dimers were higher than those in normal pregnant women (P <0.05). Conclusions The patients with eclampsia often have coagulation and fibrinolysis abnormalities. Before delivery, the co-detection of coagulation function and plasma D-dimer level is helpful for monitoring changes of coagulation and fibrinolysis in pregnant women and predicting the specific physiological status of perinatal period Caused by pathological abnormalities for the early detection and early prevention of eclampsia has important clinical value.