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恶性梗阻性黄疸是因壶腹周围肿瘤、胰头或肝门胆管肿瘤侵犯、压迫肝外胆管导致胆管内压增高,胆汁排出受阻,进而使胆红素逆流入血,引起的以皮肤巩膜黄染、尿色加重以及陶土样大便为主要临床表现的一类疾病。它会引起机体多个脏器及系统功能损伤,因此对于术前减黄是否有利于患者预后的问题存在着不少争议,由于缺少有说服力的随机数据,临床指导的发展受到限制,因而也导致了治疗上的不统一性。随着研究的深入,术前减黄的观念已发生了改变,而针对术前减黄,减黄的时机、减黄的方式及部位、减黄的程度以及对应的手术时机即成为争议的焦点。
Malignant obstructive jaundice is due to tumor around the ampulla, pancreatic head or portal hilar tumor invasion, oppression of the extrahepatic bile duct lead to increased bile duct pressure, bile excretion blocked, so that reflux of bilirubin into the blood, caused by scleral skin yellow dye , Increased urine and clay-like stool as the main clinical manifestations of a class of diseases. It causes multiple organ and systemic damage to the body. There is therefore much controversy over whether preoperative yellowing favors the prognosis of patients. Due to the lack of convincing randomized data, the development of clinical guidelines is limited and therefore Lead to the treatment of non-uniformity. With the deepening of research, the concept of preoperative reduction of yellow has changed, and for the preoperative reduction of yellow, yellow reduction of the time, the way and parts of the yellow, yellow reduction and the corresponding timing of the operation has become the focus of controversy .