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旨在研究＋Gz对微血管结构及其对大分子物质通透性的影响，探讨＋Gz对组织结构损伤的特点。16只雄性大耳白家兔随机分为4组，对照组动物暴露于＋1Gz5.min，其余3组分别暴露于＋5、＋8、＋10Gz至动物心电拉手。牛血清白蛋白（BSA）400mg／kg体重作为示踪物。暴露后对脑、心肌等11种组织进行常规组织学及超微结构观察，并用微波辐射下免疫金银染色法（IGSS）检测微血管对BSA通透性的变化。结果表明，实验组动物心肌、肝、肠及后肢皮肤等多器官做血管充血，微血管超微结构损伤及对BSA通透性增加；上述变化在脑、心肌、肠道及后肢皮肤组织内表现明显，而在肺、肾、骨骼肌等组织内则轻或不明显，表现出一定的器官特异性。
The purpose of this study was to investigate the effect of + Gz on the microvascular structure and its permeability to macromolecules, and to explore the characteristics of + Gz damage to tissue structure. Sixty-six male white rabbits were randomly divided into 4 groups. Animals in the control group were exposed to + 1Gz5.min, and the remaining 3 groups were exposed to +5, +8, +10 Gz respectively. Bovine serum albumin (BSA) 400 mg / kg body weight was used as a tracer. After exposure, 11 kinds of tissues such as brain and myocardium were observed by routine histology and ultrastructure. The changes of microvascular permeability to BSA were detected by immunogold-silver staining (IGSS) under microwave irradiation. The results showed that in experimental group, the myocardium, liver, intestine and hindlimb skin and other organs did vascular congestion, microvascular ultrastructure damage and increased permeability to BSA. The above changes were obvious in the skin tissue of brain, myocardium, intestine and hindlimb , While in the lung, kidney, skeletal muscle and other tissues were light or not obvious, showing some organ specificity.