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目的:探讨幼女小阴唇粘连的临床特点及粘连分离术后的疗效。方法:回顾性分析2019年1—9月在西安市儿童医院儿童保健中心少儿妇科门诊诊治的439例小阴唇粘连患儿的临床资料。439例患儿年龄为1.0月龄~10岁，平均15.9月龄（中位年龄12.0月龄），均行小阴唇粘连手法分离治疗，术后创面涂红霉素乳膏，并用苯扎氯铵溶液清洁外阴。结果:幼女小阴唇粘连的病因未完全明确，外阴清洁、护理不当等致反复外阴阴道炎者85.19%（374/439）,无明确诱因者14.81%（65/439）；幼女小阴唇粘连的发病平均年龄为15.9月龄，其中3月龄~3岁者占88.38%（388/439），无明显临床表现者占58.54%（257/439），在体检或清洗外阴时发现。行小阴唇粘连分离术后，全部患儿均一次分离成功，经过1周的术后护理，409例（93.17%）患儿基本痊愈，30例（6.83%，30/439）患儿复发。结论:小阴唇粘连好发于≤3岁幼女，常无明显临床症状，多在体检或清洗外阴时发现，早期诊断后行粘连手法分离的治愈率较高，复发率较低，且无严重术后并发症。“,”Objective:To analyze the clinical characteristics of infant and young girls with labial adhesions and to assess the efficacy of manual separation.Methods:Clinical data of 439 infant and young girls with labial adhesions admitted in Children Healthcare Center of Xi′an Children′s Hospital from January 2019 to September 2019 were retrospectively analyzed. All patients received treatment with manual separation. After separation, perineal cleaning and erythromycin cream were applied.Results:The etiology was associated with repeated history of vulvovaginitis due to improper cleaning and nursing of vulva in 85.19% cases(374/439), it was unclear in 14.81% (65/439). The average age of onset minora adhesions in young girls was 15.9 months old, of which 88.38% (388/439)was from 3 months to 3 years old, and 58.54%(257/439) had no obvious clinical manifestations. After treatment, the adhesions were successfully separated in all the patients, but 30(6.83%) children had recurrence one week later.Conclusion:Early manual separation can effectively improve the cure rate and reduce the recurrence rate for infant or young girls with labial adhesions.