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目的探讨不同栓塞剂行子宫动脉栓塞术治疗子宫肌瘤后的疗效、不良反应及并发症。方法 62例子宫肌瘤行选择性双侧子宫动脉插管造影栓塞治疗,其中32例用真丝线段栓塞(SS组),30例用聚乙烯醇栓塞(PVA组)。术后随访6个月,观察临床症状改变、肌瘤大小变化、术后不良反应及并发症。结果丝线组和PVA组贫血、月经量多、压迫症状均有不同程度不同改善。虽然UAE后6个月PVA组肌瘤缩小较多,但差异无统计学意义(P>0.05)。PVA组的UAE后发热率较丝线组增高(P=0.043 2),而其他不良反应及并发症两组间差异无统计学意义(P>0 05)。结论真丝线段和PVA行子宫动脉栓塞治疗子宫肌瘤均有明显疗效且不良反应发生率差别较小,是良好的UAE栓塞材料。
Objective To investigate the curative effect, side effects and complications of different embolic agents after uterine artery embolization for uterine fibroids. Methods Totally 62 cases of uterine fibroids were treated with selective bilateral uterine artery embolization and embolization, of which 32 cases were treated with silk thread embolization (SS group) and 30 cases with polyvinyl alcohol embolization (PVA group). The patients were followed up for 6 months. Changes of clinical symptoms, fibroid size, postoperative adverse reactions and complications were observed. Results In the silk group and PVA group, anemia, menorrhagia, and oppression symptoms all improved in different degrees. Although the fibroids in PVA group shrank more in the 6 months after UAE, the difference was not statistically significant (P> 0.05). The rate of post-UAE fever in PVA group was higher than that in silk thread group (P = 0.043 2), while there was no significant difference in other adverse reactions and complications between the two groups (P> 0.05). Conclusion The silk segment and PVA uterine arterial embolization have obvious curative effect on uterine fibroids and the incidence of adverse reactions is slightly different, which is a good UAE embolic material.