论文部分内容阅读
目的:总结复发性喉癌治疗的方法其效果,以提高患者的生存率和生存质量。方法:应用回顾性分析的方法,对1995年12月至2009年12月复发性喉癌56例患者资料进行分析。结果:局部复发30例,全喉切除20例,喉部分切除6例,放疗4例;区域性复发26例,全部行根治性颈清术。总的5年生存率为33.92%,局部复发组和区域性复发组5年生存率分别为53.33%和11.53%,局部复发组中喉部分切除术患者的5年生存率为50%,喉全切除术患者的5年生存率为55%,放疗4例5年随访无1例生存。结论:复发性喉癌的治疗应以外科手术治疗为主;颈淋巴结转移是影响喉癌预后的重要因素;根据复发部位选择合理的手术方式,在保证安全切缘的情况下,运用最优的手术切除和综合治疗,可有效地提高复发性喉癌患者的生存率和生存质量。
OBJECTIVE: To summarize the effectiveness of the treatment of recurrent laryngeal cancer in order to improve the survival rate and quality of life of patients. Methods: The data of 56 patients with recurrent laryngeal carcinoma from December 1995 to December 2009 were analyzed by retrospective analysis. Results: Local recurrence in 30 cases, total laryngectomy in 20 cases, partial laryngectomy in 6 cases, radiotherapy in 4 cases; regional recurrence in 26 cases, all underwent radical neck dissection. The overall 5-year survival rate was 33.92%. The 5-year survival rates in local and regional recurrence groups were 53.33% and 11.53%, respectively. The 5-year survival rate in laryngectomy patients in local recurrence group was 50% The 5-year survival rate was 55% in patients undergoing resection and 4 in 5 patients survived without radiotherapy for 5 years. Conclusion: The treatment of recurrent laryngeal cancer should be based on surgical treatment; cervical lymph node metastasis is an important factor affecting the prognosis of laryngeal cancer; according to the recurrence of the site to choose a reasonable surgical approach to ensure the safety margin, the use of optimal Surgical resection and comprehensive treatment, can effectively improve the survival rate and quality of life in patients with recurrent laryngeal cancer.