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目的观察苯那普利与伊贝沙坦治疗高血压病的疗效。方法随机将63例原发性高血压病患者分为伊贝沙坦组(32例)和苯那普利组(31例),治疗4周,观察苯那普利与伊贝沙坦的降压效果。结果治疗4周后苯那普利组17例显效、7例有效,总有效率为77.41%。伊贝沙坦组21例显效、5例有效,总有效率为81.25%。两组间差异无统计学意义(P>0.05)。结论苯那普利与伊贝沙坦降压效果、降压幅度均基本相似,对血糖、血脂、肝功能及电解质均无明显影响,苯那普利组不良反应的发生率比伊贝沙坦组高,但无统计学意义(P>0.05)。
Objective To observe the efficacy of benazepril and irbesartan in the treatment of hypertension. Methods Sixty-three patients with essential hypertension were randomly divided into two groups: ibuprofen (32 cases) and benazepril (31 cases) for 4 weeks. Benazepril and irbesartan Pressure effect. Results After 4 weeks of treatment, 17 cases were markedly effective in benazepril group, 7 cases were effective and the total effective rate was 77.41%. 21 cases in irbesartan group were effective, 5 cases were effective, the total effective rate was 81.25%. There was no significant difference between the two groups (P> 0.05). Conclusions Benazepril and irbesartan have similar antihypertensive effect and antihypertensive effect, and have no significant effect on blood glucose, blood lipid, liver function and electrolytes. The incidence of adverse reactions in benazepril group is higher than that of irbesartan Group, but not statistically significant (P> 0.05).