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目的调查广东省翁源县新生儿脐带血铅的含量,分析其影响因素,为当地优生优育政策提供科学依据。方法选取广东省韶关市翁源县妇幼保健院和新江镇卫生院作为研究现场,对所有在2011年9月1日-2012年8月31日分娩的576名孕妇进行问卷调查,同时采集新生儿脐带血标本。结果 576名新生儿脐带血铅含量为12.77~253.63μg/L,中位数和四分位数间距分别为31.96和18.37μg/L;44名(7.64%)新生儿脐带血铅含量>100μg/L;单因素分析显示,孕期住房距公路距离>50 m(OR=0.39,95%CI=0.19~0.78)、孕妇孕期平均每天走公路时间>30 min(OR=2.51,95%CI=1.30~4.84)、孕期喝咖啡(OR=4.47,95%CI=2.38~8.39)、孕期饮茶(OR=3.00,95%CI=1.60~5.62)和孕期补钙(OR=0.26,95%CI=0.13~0.52)与新生儿脐带血铅含量有关;多因素分析显示,孕期喝咖啡(OR=3.58,95%CI=1.11~11.57)和补钙(OR=0.31,95%CI=0.10~0.97)与新生儿脐带血铅含量有关。结论当地新生儿脐带血铅含量水平较高,孕妇妊娠期住宅距公路距离及其生活习惯与之相关。
Objective To investigate the content of cord blood lead in newborns in Wengyuan County of Guangdong Province and analyze its influencing factors so as to provide a scientific basis for the policy of prenatal and postnatal care. Methods A total of 576 pregnant women who gave birth between September 1, 2011 and August 31, 2012, were selected as research sites by Wengyuan County Maternal and Child Health Hospital and Xinjiang Town Health Center in Shaoguan City, Guangdong Province. Umbilical cord blood samples. Results The cord blood lead content of 576 newborns was 12.77 ~ 253.63μg / L, the median and interquartile range were 31.96 and 18.37μg / L, respectively. The lead content of cord blood of 44 neonates (7.64%) was> 100μg / L; univariate analysis showed that the distance between houses during pregnancy was> 50 m (OR = 0.39, 95% CI = 0.19-0.78) 4.84), drinking coffee during pregnancy (OR = 4.47, 95% CI = 2.38- 8.39), drinking tea during pregnancy (OR = 3.00,95% CI = 1.60-5.62) ~ 0.52) were related to cord blood lead levels in neonates. Multivariable analysis showed that coffee consumption (OR = 3.58, 95% CI = 1.11-1 11.57) and calcium supplement during pregnancy (OR = 0.31, 95% CI = 0.10-0.97) Neonatal cord blood lead levels. Conclusion The level of lead in cord blood of newborns in the local area is relatively high, and the distance between pregnant and residential areas of pregnant women is related to their distance and their living habits.