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新疆是我国食管癌高发区，尤以北疆哈萨克族为高，我们对不同民族食管癌组织内ｐ５３、ＰＣＮＡ及Ｓ１００＋在癌变过程中的变化进行了比较研究。１ 材料和方法应用免疫组化（ＬＳＡＢ）染色对１１９例食管鳞癌及癌旁组织（哈族４７例，维族３２例，汉族４１例，其他９例）
Xinjiang is a high-risk area of esophageal cancer in our country, especially in the Kazakh population in northern Xinjiang. We conducted a comparative study of p53, PCNA, and S-100+ changes in carcinogenesis of esophageal cancer tissues from different ethnic groups. 1 Materials and Methods 119 cases of esophageal squamous cell carcinoma and paracancerous tissue were studied by immunohistochemistry (LSAB) staining (47 cases of Kazakh, 32 cases of Uygur, 41 cases of Han, and 9 cases)