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目的:探讨MCV/RDW贫血分类法对孕妇缺铁性贫血的诊断价值。方法:检测200例血红蛋白(Hb)<110g/L的孕妇(孕28周以上)和对照组120名非孕期(24～29岁)健康妇女的血清铁(Fe)、红细胞平均血红蛋白量(MCH)、红细胞平均血红蛋白浓度(MCHC)、红细胞平均体积(MCV)、红细胞体积分布宽度(RDW)。按MCV/RDW贫血分类法,将孕妇组分为三组:缺铁性贫血组(RDW>13.9%)100例,隐性缺铁前期组(RDW12.5%～13.9%)40例,生理性贫血组(RDW<12.5%)60例,分别与对照组作比较。结果:缺铁性贫血组Hb、Fe、MCH、MCHC、MCV均明显低于对照组(P<0.01);RDW明显增大(P<0.01)。隐性缺铁前期组Hb、MCV明显低于对照组(P<0.01);RDW明显增大(P<0.01);Fe、MCH、MCHC、MCV、RDW与对照组差异均无统计学意义(P>0.05)。结论:MCV/RDW贫血分类法能提前检测出缺铁前期的贫血孕妇,为妊娠期各类贫血早期进行针对性治疗提供可靠的诊断依据。
Objective: To investigate the diagnostic value of MCV / RDW anemia classification in pregnant women with iron deficiency anemia. Methods: Serum iron (Fe), erythrocyte mean hemoglobin (MCH), serum creatinine (Fe) and serum creatinine were determined in 120 healthy pregnant women (24 to 29 years old) with hemoglobin (Hb) <110g / , Mean erythrocyte hemoglobin concentration (MCHC), mean corpuscular volume (MCV), and red blood cell volume distribution width (RDW). According to MCV / RDW anemia classification, pregnant women were divided into three groups: 100 in iron deficiency anemia group (RDW> 13.9%), 40 in RDW (12.5% ~ 13.9% Anemia group (RDW <12.5%) 60 cases, respectively, compared with the control group. Results: The levels of Hb, Fe, MCH, MCHC and MCV in the patients with iron deficiency anemia were significantly lower than those in the control group (P <0.01). RDW was significantly increased (P <0.01). The levels of Hb and MCV in the early iron deficiency group were significantly lower than those in the control group (P <0.01); the RDW was significantly increased (P <0.01); but there was no significant difference between the Fe, MCH, MCHC, MCV and RDW groups > 0.05). Conclusion: The MCV / RDW anemia classification method can detect the anemia pregnant women in the early stages of iron deficiency and provide a reliable basis for the targeted treatment of all kinds of anemia during pregnancy.