论文部分内容阅读
目的:随访观察20例核素131I治疗老年甲状腺功能亢进性心脏病(老年甲亢心)的疗效及甲状腺功能减退的发生率,讨论131I治疗老年甲亢心的临床应用价值。方法:20例老年甲亢心是62例老年甲亢中经临床症状、体征及实验室检查确诊(占老年甲亢32.3%),131I治疗前伴有房颤、心脏增大、心力衰竭一种或几种心脏异常,131I治疗后随访1～16年,平均随访5.4年。结果:131I治疗后痊愈19例(包括发生甲状腺功能减退者)95%,复发1例(5%);总治愈率为95%;晚发甲状腺功能减退3例(15%),亚临床甲状腺功能减退6例(45%),其中伴房颤16例经131I治疗后3～14个月转为窦性心律14例,2例房颤持续存在。结论:131I治疗老年甲亢心简便安全、经济、无痛苦、治愈率高,目前仍是治疗老年甲亢心的重要手段。
Objective: Follow-up observation of 20 cases of radionuclide 131I treatment of elderly patients with hyperthyroidism heart disease (hyperthyroidism in elderly patients) and the incidence of hypothyroidism, 131I treatment of elderly patients with hyperthyroid heart clinical value. Methods: Twenty patients with hyperthyroid heart in the elderly were diagnosed by clinical symptoms, signs and laboratory tests (accounting for 32.3% of elderly hyperthyroidism) in 62 elderly patients with hyperthyroidism. Atrial fibrillation, heart enlargement, one or several heart failure Abnormal heart, 131I treatment followed up for 1 to 16 years, an average of 5.4 years of follow-up. RESULTS: Nineteen patients (including those with hypothyroidism) recovered after 131I treatment, and one patient (5%) relapsed. The overall cure rate was 95%. Late hypothyroidism was found in 3 patients (15%), subclinical thyroid function 6 cases (45%) were reduced. Among them, 16 cases of atrial fibrillation were converted to sinus rhythm in 14 cases 3 to 14 months after 131I treatment and 2 cases of atrial fibrillation persisted. Conclusion: 131I treatment of elderly hyperthyroidism is simple and safe, economical, painless, high cure rate, is still an important means of treatment of elderly hyperthyroid heart.