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目前青霉素仍是许多感染性疾病的首选药。随着临床药学研究的深入,对其适应症、配伍、给药方法和毒副作用也有新的认识,尚未引起基层医务人员的注意。为使临床合理应用青霉素,我们复习了近年国内部分文献,特综述如下,以供同道参考。一、掌握适应症,减少耐药性青霉素类分天然青霉素和半合成青霉素两类,前者以青霉素G最常用,属窄谱杀菌剂。对大多数革兰氏阳性菌和革兰氏阴性球菌有强大杀菌作用,对螺旋体和放线菌亦有
Penicillin is still the drug of choice for many infectious diseases. With the deepening of clinical pharmacy research, its indications, compatibility, methods of administration and side effects also have new understanding, has not yet caused the attention of grass-roots medical staff. In order to make clinical use of penicillin reasonable, we review some of the domestic literature in recent years, with special reviews as follows for reference. First, to adapt to indications and reduce drug resistance Penicillin sub-natural penicillin and semi-synthetic penicillin two types, the former penicillin G most commonly used, is a narrow-spectrum fungicide. For most Gram-positive bacteria and Gram-negative bacteria have a strong bactericidal effect on spirochetes and actinomycetes also