Potential role of human visceral pleura in pleural fluid turnover

• 作 者: GAO Zhan-cheng XUE Pei-li ZHAN
• 机 构: Departments of Respiratory and Critical Care Medicine,Department of Respiratory Medicine,Department
• 出 处: 中华医学杂志（英文版）
• 发表日期: 2004年期
• 关键词: cor pulmonale left heart failure pleural fluid turnover visceral pleura

With continuing advanced research into pleural fluid turnover, the majority of scientists hold the view that pleural fluid is derived from the microvessels in parietal pleura and drained via parietal lymphatic vessels which empty into systemic veins. The lymphatic vessels that contribute to the pulmonary lymphatic circulation originate in the subpleural connective tissue, not directly from the visceral mesothelium.1 Therefore, according to the current point of view, pleural effusion absorption through the visceral pleural is normally negligible and visceral pleura, is not involved in the pleural fluid turnover.2 Our study explored the origins of pulmonary lymphatic tissues in humans and the possible effect of visceral pleural on pleural fluid turnover. We compared the incidence of pleural fluid between patients with left and right heart failure, and detected the origin and distribution of lymphatic tissues in pulmonary lymphangiopathy.