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20例咨询对象来源遗传咨询门诊和计划生育门诊,按着统一卡片,询问病史,家族史,婚姻与生育史,有毒物质接触史、全面体格检查,结合临床做必要的化验检查。凡有两次以上自然流产史,且有一次以上葡萄胎病史夫妇,均做外周血染色检查。显微镜分析G带中期染色体核型5个细胞,异常加倍并摄影,其结果20对葡萄胎患者夫妇,外周血染色体异常3例,其异常率为15%。Kajii等1977年报道了35对患葡萄胎夫妇的外周血淋巴细胞染色体检查结果,发现2例葡萄胎患者有平衡易位,发生率高于一般成人的0.3%,他们认为易位染色体的存在有可能影响减数
According to the unified card, medical records, family history, marriage and maternity history, history of exposure to toxic substances, comprehensive physical examination, and laboratory tests were performed in the same way. Where there are more than two times the history of spontaneous abortion, and more than one hydatidiform mole couple, are done in peripheral blood staining. Microscopic analysis of G cells with metaphase chromosome karyotype 5 cells, abnormal doubling and photography, the results of 20 pairs of patients with hydatidiform mole, peripheral blood chromosomal abnormalities in 3 cases, the abnormal rate was 15%. Kajii et al. (1977) reported the chromosomal examination of peripheral blood lymphocytes in 35 couples with hydatidiform moles and found that two hydatidiform mole patients had a balanced translocation, the incidence of which was 0.3% higher than that of normal adults. They considered the presence of translocated chromosomes May affect the reduction