论文部分内容阅读
实验用家兔和SD大鼠，氨基甲酸乙酯麻醉（1g／kg，ivorip）。记录隔神经或隔肌放电作为呼吸的指标。在延髓面神经后核内侧区（mNRF）细胞外记录呼吸相关神经元（RRNs）放电，在家兔所记录到的249个RRNs中，吸气神经元118个（47．4％，可分4种亚型），呼气神经元91个（36．5％，包括4种亚型），呼吸跨时相神经元40个（16．1％，包括E－I和I－E）。在大鼠所记录到的153个RRNs中，吸气神经元68个（44.5％），呼气神经元55个（35．9／），呼吸跨时相神经元30个（19．6％），在mNRF分布有较多的呼气-吸气跨时相神经元（E－IPS），这类神经元放电总是先于隔神经吸气性放电，可能在基本呼吸节律发生中起重要作用。
Experimental rabbits and SD rats were anesthetized with urethane (1 g / kg, ivorip). Mesenteric or septal discharges were recorded as indicators of respiration. Respiratory related neurons (RRNs) were recorded extracellularly in medial nucleus of medulla oblongata (mNRF). Among the 249 RRNs recorded in rabbits, 118 (47.4% 91 (36.5%, including 4 subtypes) of exhaled neurons, and respiratory synaptic neurons 40 (16.1%, including E-I and I-E). Among the 153 RRNs recorded in rats, 68 (44.5%) were inspiratory neurons, 35 (35.9 /) expired neurons and 30 (19.6%) were respiratory interphase neurons , There were more exhaled-inspiratory interphase neurons (E-IPS) in the mNRF distribution. Such neuronal discharge always preceded the septal nerve inspiratory discharge and may play an important role in the occurrence of basic respiratory rhythm .