论文部分内容阅读
目的:探讨替硝唑合剂(以替硝唑为主药,辅以地塞米松、头孢噻啶)对牙体牙髓病的治疗效果和安全性。方法:随机选取我院2013-2015年收治的90例牙体牙髓病患者并将其随机均分为观察组和对照组。观察组患者用替硝唑合剂联合甲醛甲酚暂封一周并于一周后进行永久填充治疗,对照组患者用甲醛甲酚暂封一周并于一周后进行永久填充治疗。两组患者治疗周期均为1周。对比两组患者的临床总有效率、临床症状改善情况、6个月内的复发情况及不良反应的发生情况。结果:暂封一周后,观察组患者的总体有效率(97.8%)显著高于对照组患者(82.4%)(P<0.05)。观察组6个月内的病症复发率为2.2%,而对照组患者的复发率为13.3%,显著高于观察组(P<0.05),而观察组患者不良反应发生率(13.3%)显著低于对照组(77.8%)(P<0.05)。结论:替硝唑合剂治疗牙体牙髓病具有较好的疗效和安全性,且能有效控制病情复发。
Objective: To investigate the therapeutic effect and safety of tinidazole mixture (tinidazole as main drug, combined with dexamethasone and ceftizoxime) on dental pulp disease. Methods: Ninety cases of dental pulp diseases were randomly selected in our hospital from 2013 to 2015 and randomly divided into observation group and control group. Patients in the observation group were treated with tinidazole and formaldehyde for one week and permanently infused for one week. Patients in the control group were treated with formaldehyde for one week and permanently infused in one week. The two groups of patients were treated for one week. Compare the total effective rate of two groups of patients, clinical symptoms, recurrence within 6 months and the occurrence of adverse reactions. Results: After a week of temporary closure, the overall effective rate in the observation group (97.8%) was significantly higher than that in the control group (82.4%) (P <0.05). The recurrence rate was 2.2% in the observation group within 6 months compared with 13.3% in the control group (P <0.05), while the adverse reaction rate in the observation group (13.3%) was significantly lower In the control group (77.8%) (P <0.05). Conclusion: Tinidazole mixture has good efficacy and safety in the treatment of dental pulp disease, and can effectively control the recurrence of the disease.