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目的分析巢湖地区孕早期妇女弓形虫、风疹病毒、巨细胞病毒、单纯疱疹病毒即TORCH的检测结果,探讨其临床意义。方法采用化学发光免疫分析法对5028例孕妇TORCH-Ig M抗体和TORCH-Ig G抗体进行检测分析。结果 HSV-Ig M和HSV-Ig G阳性率最高,差异有统计学意义(P<0.05);因CMV感染导致的不良妊娠发生率为46.94%(23/49),与其他病毒感染导致的不良妊娠相比有统计学意义(P<0.05);不良妊娠结局表现中,流产发生率为67.35%(33/49),与其他不良妊娠结局表现相比,差异有统计学意义。结论巢湖地区孕早期妇女存在一定的TORCH阳性率,TORCH感染是不良妊娠结局的重要危险因素之一,因此在孕早期或孕前进行TORCH检测对指导本地区优生优育工作及提高新生儿人口素质具有重要指导意义。
Objective To analyze the detection results of Toxoplasma gondii, rubella virus, cytomegalovirus and herpes simplex virus (TORCH) in pregnant women in the first trimester of Chaohu, and to explore its clinical significance. Methods 5028 pregnant women with TORCH-Ig M antibody and TORCH-Ig G antibody were detected by chemiluminescence immunoassay. Results The positive rate of HSV-Ig M and HSV-Ig G was the highest (P <0.05). The incidence of adverse pregnancy caused by CMV infection was 46.94% (23/49), which was significantly different from other virus infections (P <0.05). The incidence of miscarriage was 67.35% (33/49) in adverse pregnancy outcomes, which was significantly different from other adverse pregnancy outcomes. Conclusions There is a positive rate of TORCH in the pregnant women in the first trimester of Chaohu region. TORCH infection is one of the important risk factors of adverse pregnancy outcomes. Therefore, TORCH detection in early pregnancy or pre-pregnancy is important to guide the prenatal and postnatal care in the region and improve the quality of neonates Guiding significance.