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本文测定50例经脉冠造影确诊的冠心病(CHD)患者的血液流变学指标。按冠脉狭窄程度将患者分为两组。冠脉主支狭窄<50%组5.755S~(-1)切变率的η_b、η_p、Fb明显高于正常对照组(P均<0.05)。冠脉主支狭窄>50%组5.75~1155~(-1)切变率的η_b、η_p、Fb、HCT这EMT均显著高于正常对照组(P<0.05~0.01);其中23、46、1155~(-1)切交率的η_b、HCT也明显高于冠脉狭窄<50%组(P<0.05~0.01)。23、46、115 S~(-1)切变率的η_b与冠脉狭窄程度正相关(r=0.37~0.41,P<0.05)。提示冠脉狭窄愈严重,血液流变学改变愈明显;测定η_b有助于对冠脉狭窄程度的判断。
In this paper, 50 patients with coronary heart disease (CHD) confirmed by transcoronary angiography hemorheology index. According to the degree of coronary stenosis patients were divided into two groups. The η_b, η_p, Fb of 5.755S ~ (-1) shear rate in the coronary artery stenosis less than 50% were significantly higher than those in the normal control group (all P <0.05). The EMTs of η_b, η_p, Fb and HCT at the shear rate of 5.75 ~ 1155 ~ (-1) in the coronary artery with stenosis> 50% were significantly higher than those in the normal control group (P <0.05 ~ 0.01) The η_b and HCT at 1155 ~ (-1) were significantly higher than that in coronary stenosis <50% (P <0.05 ~ 0.01). The η_b of 23,46,115 S ~ (-1) shear rate was positively correlated with the degree of coronary artery stenosis (r = 0.37 ~ 0.41, P <0.05). Tip more severe coronary stenosis, the more obvious changes in blood rheology; measured η_b help determine the extent of coronary stenosis.