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分析海门市1990～1996年原发性肝癌死亡资料,显示该地区肝癌的总死亡率为61.85/10万,男女死亡性别比为3:1,男性肝癌死亡率在30岁前较低,以后急剧上升,至50岁组进入高峰,女性的死亡年龄和高峰较男性推迟10年左右;对1006例肝癌死亡病例和92例现症肝癌患者1:1配对调查结果,显示肝癌病例中HBsAg阳性率为71.27％,是当地自然人群的8倍,在HBsAg阳性的肝癌病例中有慢肝病史者占61.48％;存活92例肝癌病例中HBsAg阳性率58.70％,抗-HCV阳性率16.30％,HBsAg和抗-HCV的混合感染率11.96％,与对照组相比有显著性差异(P<0.01);资料还表明,肝癌有明显的家庭聚集性,家系中有二个以上肝癌的占调查对象的40.29％,提示肝癌高发区,男性30岁、女性40岁以上,HBsAg阳性或抗-HCV阳性或慢肝病史或肝癌家族史的对象是肝癌的高危人群。
Analysis of the mortality data of primary liver cancer in Haimen City from 1990 to 1996 shows that the total mortality rate of liver cancer in the region is 61.85 per 100,000. The sex ratio of males and females is 3:1. The mortality rate of male liver cancer is low before the age of 30. Ascended to the peak of the 50-year-old group. The age and the peak of death of women were delayed by about 10 years compared with men. The 1:1 paired survey of 1006 liver cancer deaths and 92 current-onset liver cancer patients showed that the positive rate of HBsAg was found in liver cancer cases. 71.27% was 8 times that of the local natural population. 61.48% of patients with HBsAg-positive liver cancer had a history of chronic liver disease; HBsAg positive rate was 58.70% in patients with surviving 92 cases of liver cancer; anti-HCV positive rate was 16.30%; HBsAg and resistance The mixed infection rate of HCV was 11.96%, which was significantly different from that of the control group (P<0.01). The data also showed that there was a significant family aggregation of liver cancer. There were two or more liver cancers in the family who accounted for 40.29% of the surveyed subjects. The high-risk population of high-risk HCC patients was identified in high-risk areas of liver cancer, men 30 years of age, women more than 40 years of age, HBsAg-positive or anti-HCV positive or slow liver disease or family history of liver cancer.