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目的:测定A群脑膜炎球菌多糖疫苗培养基有效氨基酸;方法:分析发酵后游离氨基酸的变化;结果:半胱氨酸完全消失,色氨酸减少,其余游离氨基酸均增加;结论:半胱氨酸和色氨酸为A群脑膜炎球菌多糖疫苗培养基有效氨基酸。
OBJECTIVE: To determine the effective amino acids in the meningococcal polysaccharide vaccine group A. Methods: The changes of free amino acids after fermentation were analyzed. Results: The disappearance of cysteine and the decrease of tryptophan and the increase of other free amino acids were observed. Conclusion: Cysteamine Acid and tryptophan are effective amino acids in the meningococcal polysaccharide vaccine group A.