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目的对甲硝唑治疗牙周组织病的临床疗效进行深入探讨以及仔细研究。方法选择本院2010年9月~2012年3月收治的中重度牙周炎患者有240例,分别为观察组和对照组,其中,观察组有120例患者,采用局部甲硝唑缓释药膜并且配合基础治疗;对照组有120例患者,采用口服甲硝唑片配合基础治疗,对两组患者的临床症状改善情况进行仔细的比较,评价其治疗效果。结果对本院的两组患者进行科学的治疗后,通常经过临床症状进行治疗都有显著的改善作用,治疗前相比较其差异均有统计学意义(P<0.05);观察组患者经过科学的治疗后,症状有所改善,并且对照组的疗效显著高于观察组,其差异具有统计学意义(P<0.05);观察组的总有效率为97.22%,对照组的总有效率为80.28%,差异具有统计学意义(P<0.05)。结论在治疗牙周组织病过程中,甲硝唑是相对理想的抗菌药物,采用甲硝唑缓释药膜进行局部治疗,其操作相对简便、用药剂量较小、副作用相对少、并且疗效显著,值得临床推广以及应用。
Objective To investigate the clinical efficacy of metronidazole in the treatment of periodontal disease and to study it in detail. Methods Choose our hospital from September 2010 to March 2012 in patients with moderate to severe periodontitis were 240 cases, respectively, the observation group and the control group, of which 120 cases in the observation group were treated with local metronidazole sustained release drug Membrane and with the basis of treatment; control group of 120 patients, the use of oral metronidazole tablets with basic treatment, the two groups of patients to improve the clinical symptoms were carefully compared to evaluate the therapeutic effect. Results After treatment of two groups of patients in our hospital, the clinical symptoms were usually treated with significant improvement (P <0.05), and the difference between the two groups before treatment was statistically significant After treatment, the symptoms improved, and the efficacy of the control group was significantly higher than the observation group, the difference was statistically significant (P <0.05); the total effective rate was 97.22% in the observation group and 80.28% in the control group , The difference was statistically significant (P <0.05). Conclusion Metronidazole is a relatively ideal antimicrobial agent in the treatment of periodontal disease. Metronidazole sustained-release membrane is used for local treatment. It has the advantages of relatively simple operation, less dosage, fewer side effects and significant curative effect. Worth clinical promotion and application.