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目的分析2014年北京市顺义区健康人群乙型脑炎抗体水平特征及影响因素。方法按照随机抽样的方法抽取顺义区7个乡镇街道作为调查点,选择在当地连续居住6个月以上的健康人群共243人,采用反向被动血凝抑制方法测定乙脑中和抗体,抗体滴度≥1∶10判断为阳性。结果健康人群乙脑抗体监测阳性率为83.95%,高于全市平均水平(74.76%),差异有统计学意义(χ~2=11.541,P<0.05)。<1岁组乙脑抗体阳性率最低,不同年龄组乙脑抗体阳性率差异有统计学意义(χ~2=57.953,P<0.05);民工、家务及待业者乙脑抗体阳性率最高,不同职业人群乙脑抗体阳性率水平差异有统计学意义(χ~2=35.081,P<0.05)。结论顺义区已形成有效的免疫屏障,不易发生乙脑流行。但随着北京市城市化建设的推进,媒介蚊虫的活动范围可能发生改变,人群自然感染机会下降,同时应做好防蚊灭蚊工作,防止乙脑流行。
Objective To analyze the level and influencing factors of Japanese encephalitis antibody in healthy population in Shunyi District of Beijing in 2014. Methods According to the random sampling method, 7 townships and towns in Shunyi District were selected as the survey sites, 243 healthy people who lived continuously for more than 6 months in this area were selected, and the neutralizing antibody against JE and the antibody were detected by reverse passive hemagglutination inhibition Degree ≥ 1:10 judged as positive. Results The positive rate of JE antibody in healthy population was 83.95%, higher than the average level in the city (74.76%). The difference was statistically significant (χ ~ 2 = 11.541, P <0.05). The positive rate of Japanese encephalitis B was lower than 1 year old (P <0.05), while the positive rate of Japanese Encephalitis B was the highest The positive rate of Japanese encephalitis B in the occupational population was statistically significant (χ ~ 2 = 35.081, P <0.05). Conclusion Shunyi District has formed an effective immune barrier, is not prone to Japanese encephalitis. However, with the advancing of urbanization in Beijing, the scope of activities of media mosquitoes may change, and people’s chance of natural infection declines. At the same time, mosquito control and mosquito control should be well done to prevent the epidemic of Japanese encephalitis.