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患者女性,19岁。因高热,头剧痛、呕吐频繁呈喷射状,并经脑脊液检查,确诊为流行性脑膜炎入院。既往无肾病史。入院后即给氧,静脉滴注磺胺嘧啶、青霉素G钠抗感染,并用20％甘露醇200ml与50％葡萄糖60ml每4小时交替静推一次。第二天因尿检出结晶而停用磺胺嘧啶,改用氯霉素。第三天甘露醇改150ml/次,治疗至第六天,病人出现血尿,镜检尿RBC+++～++++,蛋白+,未见管型。CO_2CP45Vol％,BUN32mg/dl,每日尿量约1500ml。血尿持续至第九天,考虑为甘露醇所致,立即停用,改用利尿剂,血
Patient female, 19 years old. Due to high fever, severe pain, vomiting were jet-like, and cerebrospinal fluid examination, diagnosed as epidemic meningitis admitted. No past history of kidney disease. After admission to give oxygen, intravenous infusion of sulfadiazine, penicillin G sodium anti-infective, and with 20% mannitol 200ml and 50% glucose 60ml every 4 hours alternating with a static push. The next day due to urine crystallization stopped using sulfadiazine, switch to chloramphenicol. Mannitol on the third day to change 150ml / times, until the sixth day of treatment, the patient hematuria, microscopic urine RBC +++ ~ ++++, protein +, no tube. CO_2CP45Vol%, BUN32mg / dl, daily urine output of about 1500ml. Hematuria continued until the ninth day, considered as mannitol, immediately disabled, switch to diuretics, blood