论文部分内容阅读
[背景]邻苯二甲酸酯存在于许多个人护理和工业产品中,但以前没有报道表明其存在于美国食品中。邻苯二甲酸盐是广泛存在的人工合成的化合物,因此很难测量其在食品中的痕量水平。邻苯二甲酸酯与内分泌紊乱和发育改变相关联。[目的]首次报告美国食品中邻苯二甲酸酯的浓度,具体而言是在纽约州奥尔巴尼购买的72份食物样本中9种邻苯二甲酸酯类物质的水平,并将这些结果与其他国家的相关研究进行比较,估计膳食邻苯二甲酸盐的摄入量。[方法]采用购自纽约州超市经常食用的食物作为方便抽样样本。使用气相色谱-质谱法分析这些食物。用食物食用率和该种食物中邻苯二甲酸盐浓度的乘积来估计邻苯二甲酸盐膳食摄入量。[结果]食物中各邻苯二甲酸酯类物质的检出率范围从邻苯二甲酸二环己酯(DCHP)的6%到邻苯二甲酸二-2-乙基己酯(DEHP)的74%。在除牛肉以外的所有食品中,DEHP是浓度最高的邻苯二甲酸酯[在牛肉中,邻苯二甲酸二正辛酯(DnOP)是浓度最高的邻苯二甲酸酯],猪肉中的平均浓度估计值在所有食物组中最高(平均300ng/g,最大为1158ng/g)。成人摄入估计平均值范围从0.004μg(/kg.d)邻苯二甲酸二甲酯(DMP)至0.673μg(/kg.d)DEHP。[结论]邻苯二甲酸酯广泛存在于美国食物中,虽然这项研究中的邻苯二甲酸酯个体摄入估计值比美国环境保护局的参考剂量低一个数量级,但对邻苯二甲酸酯的累积暴露仍需要关注,同时需要进行更具代表性的美国食品调查。
[Background] Phthalates are found in many personal care and industrial products, but have not been previously reported to show their presence in US foodstuffs. Phthalates are widely available synthetic compounds, making it difficult to measure trace levels in foods. Phthalates are associated with endocrine disorders and developmental changes. [Purpose] To report for the first time the concentration of phthalates in US foods, specifically the levels of nine phthalates in 72 food samples purchased at Albany, New York, and compare these results with other National research is compared to estimate dietary phthalate intake. [Method] Foods purchased regularly from supermarkets in New York State were used as convenient sampling samples. These foods were analyzed using gas chromatography-mass spectrometry. Phytate dietary intake is estimated as the product of food consumption and the phthalate concentration in the food. [Result] The detection rate of each phthalate in food ranged from 6% of dicyclohexyl phthalate (DCHP) to 2-ethylhexyl phthalate (DEHP) of 74%. Of all the foods except beef, DEHP is the highest concentration of phthalates (DnOP is the highest concentration of phthalate in beef), pork The average concentration estimate was highest in all food groups (average 300 ng / g, maximum 1158 ng / g). Estimated adult intake averaged from 0.004 μg (/ kg.d) dimethyl phthalate (DMP) to 0.673 μg (/ kg.d) DEHP. [Conclusion] Phthalates are widely present in American food. Although the estimated individual intake of phthalates in this study is one order of magnitude lower than the reference dose of the US Environmental Protection Agency, Cumulative exposure to formates remains to be seen, as is the need for more representative US food surveys.