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目的:分析并总结百草枯中毒的临床特点及有效救治方法,以降低死亡率,提高抢救成功率。方法:对我院2008年1月—2011年2月收治的19例百草枯中毒患者的临床病例进行回顾分析。结果:19例百草枯中毒患者均采取了洗胃、导泻、血液灌流、吸氧、抗氧化及激素等综合治疗措施,其中病情好转者14例,治疗无效死亡者5例,4例放弃治疗。5例死亡患者中,1例因呼吸衰竭而死亡,其他4例为多脏器功能衰竭而死亡,治疗显效率73.7%,无效率为26.3%。结论:解救百草枯中毒必须分秒必争,首先应积极进行彻底洗胃,其次进行导泻、灌肠、血液灌流、抗肺组织纤维化等综合治疗,以尽快清除各器官组织中的毒物,降低病死率。
Objective: To analyze and summarize the clinical characteristics of paraquat poisoning and effective treatment methods to reduce mortality and improve the success rate of rescue. Methods: The clinical data of 19 cases of paraquat poisoning admitted to our hospital from January 2008 to February 2011 were retrospectively analyzed. Results: 19 cases of paraquat poisoning patients were taken gastric lavage, cathartic, hemoperfusion, oxygen, antioxidants and hormones and other comprehensive treatment measures, including 14 cases of improved condition, treatment ineffective death in 5 cases, 4 cases give up treatment . Of the 5 deaths, 1 died of respiratory failure and the other 4 died of multiple organ failure. The effective rate was 73.7% and the ineffective rate was 26.3%. Conclusion: Paraquat poisoning must be solved every second. First, gastric lavage should be actively carried out. Second, cathartic cats, enema, hemoperfusion and anti-pulmonary fibrosis should be treated comprehensively to remove the poison from organs and reduce mortality.