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青霉素类药物在部队基层医院应用十分普遍,本院内科1998～2005年使用青霉素类药1198例。其中不合理用药328例(27.4%)。现简述几个应注意的问题。1 不宜用葡萄糖液作溶媒使用葡萄糖作溶媒共32例,占9.8%。葡萄糖液对青霉素的β内酰胺键具有催化分解作用,葡萄糖溶液偏酸性,增加青霉素钠的水解,浓度愈高愈不稳定,故一般用0.9%氯化钠注射液作溶媒。如属必需则应在短时间内滴完。
Penicillin drugs are widely used in the army grass-roots hospitals, hospital medicine from 1998 to 2005, 1198 cases of penicillin drugs. Among them, 328 cases were irrational (27.4%). Here are a few issues that should be noted. 1 glucose solution should not be used as a vehicle for glucose in a total of 32 cases of solvent, accounting for 9.8%. Glucose solution of penicillin β-lactam bond catalytic decomposition, acidic glucose solution to increase the hydrolysis of penicillin sodium, the higher the concentration of the more unstable, it is generally used 0.9% sodium chloride injection as a vehicle. If necessary, it should be dropped in a short time.