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接受普萘洛尔治疗血管瘤的儿童越来越多,临床医生应了解药物的不良反应,并为家长提供足够的科普信息,以达到安全用药的目的。法国研究者自2010~2013年进行了一项最终包括906例婴幼儿使用普萘洛尔治疗血管瘤的安全性研究,患儿每月随访,连续24个月。普荼洛尔平均剂量为2mg/kg/d,疗程中位数为198 d。在完成全部治疗的患儿中,83.7%的患儿家长认为效果满意,5.8%的患儿因为药品不良反应而中止治疗。总体而言,8.8%的儿童
Children receiving propranolol hemangioma more and more, clinicians should understand the adverse drug reactions, and provide parents with enough popular science information, in order to achieve the purpose of safe medication. French researchers conducted a safety study that ultimately included propranolol in 906 infants and young children for the treatment of hemangiomas from 2010 to 2013. The children were followed up every month for 24 months. The average dose of Praxel was 2mg / kg / d, the median of 198 days. Among the children who completed the full treatment, 83.7% of the children felt the results were satisfactory and 5.8% of the children stopped treatment because of adverse drug reactions. Overall, 8.8% of children