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本文向儿科医师介绍了如何使用这种疫苗的问题。使用水痘疫苗的目的是:(1)保护正常儿童,预防水痘并发症;(2)保护正常成人,预防水痘并发症;(3)保护免疫抑制的儿童(特别是白血病患儿),预防播散性水痘。日本首先将OKA株水痘疫苗进行临床试验,10年随访资料显示,对水痘的体液免疫和细胞免疫持续存在。接种疫苗后的带状疱疹发生率不比水痘自然感染后的发生率高。美国将它应用于白血病患者和正常人群。本文提供有关美国制造的疫苗和研究情况。临床反应仅有低热和轻微的斑丘疹,其平均发生率大约为10%。尚无正常儿童接种后
This article describes to pediatricians how to use this vaccine. The purpose of using the varicella vaccine is to (1) protect normal children against the complications of chickenpox, (2) protect normal adults against the complications of chickenpox, (3) protect immunosuppressed children (especially children with leukemia) and prevent dissemination Sexual chicken pox. Japan first of all, OKA strains of chicken pox vaccine for clinical trials, 10-year follow-up data show that the constant presence of humoral and cellular immunity to chickenpox. The incidence of shingles after vaccination is not higher than the incidence of natural infection with chickenpox. The United States applies it to patients with leukemia and normal population. This article provides information on vaccines and research conducted in the United States. The clinical response is only mild fever and mild rash, the average incidence of about 10%. No normal children after vaccination