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目的:分析了在我院就诊的妊娠期间甲状腺功能亢进孕妇的临床资料,讨论妊娠合并甲状腺功能亢进对妊娠结局的影响。方法:2008年1月～2012年12月在我院分娩的妊娠期合并甲亢共64例,根据治疗情况分为2组,分为甲亢治疗组41例,与甲亢未治疗组23例,对64例孕妇分娩前查甲功,分娩后立即取脐带血测甲功,记录出生体重、胎龄、性别、Apgar评分、分娩方式,观察新生儿心率、呼吸、神经系统体征、甲状腺有无肿大等甲亢表现。结果:甲亢未治疗组与治疗组相比,先兆子痫、充血性心衰、甲亢危象、胎盘早剥发生率明显升高,2组比较差异有统计学意义,P<0.05,产褥感染的发生率无明显差异,P>0.05;甲亢治疗组与正常组相比,先兆子痫、充血性心衰、甲亢危象、胎盘早剥、产褥感染的发生率2组比较差异无统计学意义,P>0.05。甲亢未治疗组与治疗组相比,早产儿发生率、小于胎龄儿发生率明显升高,新生儿出生体重减低,新生儿胎龄小,2组比较差异有统计学意义,P<0.05;甲亢治疗组与正常组相比,早产儿发生率、小于胎龄儿发生率,新生儿出生体重,新生儿胎龄2组比较差异无统计学意义,P>0.05。结论:加强对妊娠期甲亢患者的管理,有助于改善母儿预后。
OBJECTIVE: To analyze the clinical data of pregnant women with hyperthyroidism during pregnancy in our hospital and discuss the effect of pregnancy complicated with hyperthyroidism on pregnancy outcome. Methods: From January 2008 to December 2012, 64 cases of hyperthyroidism during pregnancy in our hospital were divided into two groups according to the treatment: 41 cases were treated with hyperthyroidism, 23 cases were treated with hyperthyroidism and 23 cases were treated with hyperthyroidism Cases of pregnant women before delivery check acupuncture, umbilical cord blood taken immediately after delivery measured meq, birth weight, gestational age, gender, Apgar score, mode of delivery, observation of neonatal heart rate, respiration, neurological signs, thyroid enlargement, etc. Hyperthyroidism performance. Results: Compared with the untreated group, the incidence of preeclampsia, congestive heart failure, hyperthyroidism crisis and placental abruption significantly increased in untreated hyperthyroidism group. There was significant difference between the two groups (P <0.05), puerperal infection The incidence of preeclampsia, congestive heart failure, hyperthyroidism crisis, placental abruption, the incidence of puerperal infection was no significant difference between the two groups Significance, P> 0.05. Compared with the treatment group, the incidence of premature babies, the incidence of premature babies less than gestational age, the birth weight of newborns and the gestational age of newborn babies were lower than those of the untreated ones. There was significant difference between the two groups (P <0.05). Hyperthyroidism treatment group compared with the normal group, the incidence of preterm children, less than the incidence of gestational age, newborn birth weight, neonatal gestational age group 2 was no significant difference (P> 0.05). Conclusion: To strengthen the management of patients with hyperthyroidism during pregnancy, will help to improve the prognosis of maternal and child.