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目的探讨扩张型心肌病患者血浆脑钠肽(BNP)与心功能衰竭之间的关系,及不同阶段的扩张型心肌病患者血浆BNP的变化情况。方法将16例扩张型心肌病患者及30例健康体检者,分别进行血浆BNP检测及心脏超声心动图检测,进行对比分析。结果心脏彩色超声心动图检测16例均为中重度扩张型心肌病患者,其血浆BNP结果显示与心肌扩张度成正比,健康体检者与扩张型心肌病患者的血浆BNP结果显示,血浆BNP能够明确反应出心脏的功能,与心功能衰竭程度成正比。结论扩张性心肌病患者血浆BNP水平能预测心功能的情况,同时可以表达扩张型心肌病患者的病情程度。
Objective To investigate the relationship between plasma brain natriuretic peptide (BNP) and heart failure in patients with dilated cardiomyopathy and the changes of plasma BNP in patients with dilated cardiomyopathy at different stages. Methods Twenty-six patients with dilated cardiomyopathy and 30 healthy subjects were examined by plasma BNP and echocardiography, respectively, for comparative analysis. Results Echocardiography in 16 patients with moderate to severe dilated cardiomyopathy were detected. The results of plasma BNP showed that it was directly proportional to the degree of myocardial dilatation. The results of plasma BNP in healthy and dilated cardiomyopathy patients showed that plasma BNP could be clearly identified Reflects the function of the heart, is proportional to the extent of heart failure. Conclusions Plasma BNP level in patients with dilated cardiomyopathy can predict cardiac function and at the same time can express the severity of dilated cardiomyopathy.