生长激素和胰岛素对胎儿躯体生长发育的影响

• 作 者: 叶大勋 倪晓燕 刘戈力
• 机 构: 天津医学院附属医院儿科,天津医学院附属医院儿科,天津医学院附属医院儿科,
• 出 处: 天津医药
• 发表日期: 1991年10期
• 关键词: 新生儿脐血 生长发育 孕妇静脉血 头围 间接作用 呼吸窘迫综合征 生长障碍 生长因子 出生后 健康孕妇

本文用放免方法测定了92例健康孕妇静脉血及其新生儿脐血的生长激素(GH),胰岛素(INS)水平,并测量了新生儿的出生体重、身长和头围。结果显示,脐血 GH 水平明显高于母血,且与母血无相关性,脐血 INS 水平明显低子母血,亦与母血 INS 水平无相关性。胎儿的身长、体重与脐血 GH 水平呈负相关,与脐血 INS 水平呈正相关。本文结果表明,GH 对胎儿躯体生长发育不起决定作用,INS 可以通过直接或间接作用对胎儿宫内生长发育产生影响,是重要的“生长因子”。

In this paper, the levels of growth hormone (GH) and insulin (INS) in venous blood of 92 healthy pregnant women and their newborns were measured by radioimmunoassay. The birth weight, body length and head circumference were measured. The results showed that umbilical blood GH levels were significantly higher than maternal blood, and no correlation with maternal blood cord blood umbilical cord blood INS significantly low maternal blood, but also with maternal blood INS levels were not related. Fetal body length, body weight and umbilical cord blood GH levels was negatively correlated with cord blood INS levels were positively correlated. The results show that GH can not play a decisive role in the growth and development of the fetal body, and INS may play an important role in growth and development of the fetus through direct or indirect effects and is an important “growth factor”.