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我们从1975～84年4月采用以门诊为主的全程化疗管理方式,以RFP、EB、INH治疗慢性传染源83例。目的在于探讨对这类病例的疗效及其副作用。本组病例均经多种抗结核药物长期治疗(未用过RFP、EMB)痰菌持续阳性。平均年龄54岁,60岁以上33例(40.7％)。病程平均15年4个月,5年以上者69例(85.2％)。治疗前持续痰菌阳性平均5年5个月。慢性纤维空洞型53例(65.4％),浸润型28例(34.6％)。其中毁损肺15例、并存慢支30例、肺气肿33例、反复继发肺部感染26例、支扩7例,肺大疱4
From 1975 to April 84, we adopted a full-course chemotherapy management mode based on outpatient treatment, and treated 83 cases of chronic infection source with RFP, EB and INH. The purpose is to explore the efficacy of these cases and their side effects. The patients were long-term treatment by a variety of anti-TB drugs (not used RFP, EMB) sputum continuous positive. The average age of 54 years old, 33 cases over the age of 60 (40.7%). The course of disease was 15 years and 4 months on average, 69 cases (85.2%) over 5 years. Continued sputum positive before treatment average of 5 years and 5 months. There were 53 cases (65.4%) of chronic fibrous cavities and 28 cases (34.6%) of infiltrative types. Among them, 15 cases were damaged lungs, 30 cases were complicated with chronic bronchitis, 33 cases were emphysema, 26 cases were repeated secondary pulmonary infection, 7 cases were extended and bulla 4