论文部分内容阅读
目的:了解输血前4项血清感染性指标的检测在预防输血相关感染性疾病的作用。方法用酶联免疫吸附法对受血者输血前血液进行乙肝表面抗原(HBs Ag)、艾滋病病毒(HIV)抗体、丙肝病毒(HCV)抗体及梅毒(TP)抗体4项血清学指标检测分析。结果:本组3000例患者中,HBs Ag阳性412例,阳性率为13.73%。抗HCV阳性81例,阳性率为2.7%。TP特异性抗体阳性14例,阳性率为0.47%,抗HIV抗体阳性3例,阳性率为0.10%。其中HBs Ag、抗HCV双重阳性为15例,HBs Ag、TP抗体双重阳性为1例。不同科室的患者均有输血相关病原学标志物检出,HBs Ag、抗HCV遍布于各科室,检出率较高;HBs Ag、抗HCV阳性患者主要集中在消化科和感染病科,抗HCV阳性多为输血次数多,透析患者。抗HIV抗体、TP特异性抗体阳性者多集中在性乱和吸毒人群。结论:部分患者在输血前已感染相关传染性疾病,血清感染性指标的检测,可以有效预防输血相关传染病的传播和进一步感染,最大限度减少临床输血风险。
OBJECTIVE: To understand the role of the detection of 4 serovars before blood transfusion in preventing transfusion-related infectious diseases. Methods Serum levels of HBs Ag, HIV, HCV and TP were measured by enzyme-linked immunosorbent assay before transfusion. Results: Of the 3000 patients in this group, HBs Ag positive 412 cases, the positive rate was 13.73%. The anti-HCV positive 81 cases, the positive rate was 2.7%. 14 cases of TP-specific antibody positive rate of 0.47%, anti-HIV antibody-positive in 3 cases, the positive rate was 0.10%. Among them, HBsAg and anti-HCV double positive in 15 cases, HBsAg, TP double antibody positive in 1 case. Patients in different departments have blood transfusion-related pathogenic markers detected, HBsAg, anti-HCV throughout the departments, the detection rate is higher; HBsAg, anti-HCV-positive patients are mainly concentrated in the Department of Gastroenterology and Infectious Diseases, anti-HCV Mostly positive for the number of transfusions, dialysis patients. Anti-HIV antibodies, TP-specific antibody-positive and more concentrated in sexual abuse and drug users. Conclusion: Some patients have been infected with infectious diseases before transfusion, and the detection of serum infectious index can effectively prevent the transmission and further infection of transfusion-related infectious diseases and minimize the risk of clinical transfusion.