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本文中作者比较了含左旋18甲(LNG)或地索高诺酮(DOG)的三种新型OC,用药前及用药6个月后,口服葡萄糖耐量试验期间血中葡萄糖(BG)、丙酮酸、胰岛素、胰高血糖素及红细胞胰岛素受体水平的变化。研究对象为40名健健年轻妇女,她们的年龄、身高和体重相仿,无糖尿病家族史,体重在其标准体重±15%范围内。所有研究对象红细胞平均寿命无异常,网织细胞计数正常,以前未用过OC或已停用OC 8周以上。参与研究前于经前7天作口服葡萄糖耐量试验(OGTT)为对照。试验前3天每天饮食中含碳水化合物至少250克。以后每例随
In this paper, we compared three new forms of OC with either LNG or DOG. Before and 6 months after drug administration, blood glucose (BG), pyruvate , Insulin, glucagon and erythrocyte insulin receptor levels. The subjects were 40 healthy young women who had similar age, height, and weight, had a family history of no diabetes, and were within ± 15% of their standard body weight. The average life expectancy of erythrocytes in all subjects was normal, the reticulocyte count was normal, OC had not been used before, or OC had been discontinued for more than 8 weeks. Oral glucose tolerance test (OGTT) was used as control before participating in the study for 7 days. Three days before the test daily diet contains carbohydrates at least 250 grams. After each case with