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为探讨亚临床状态维生素Ａ（ＶＡ）缺乏对儿童哮喘、反复呼吸道感染（ＲＡＩ）的影响，采用微量荧光测定法对２２例哮喘患儿，２７例ＲＡＩ患儿及３５例健康儿童血清ＶＡ水平进行了检测。结果为各年龄组哮喘患儿、ＲＡＩ患儿血清ＶＡ水平明显低于正常同龄儿对照组，Ｐ＜００５。儿童哮喘及反复呼吸道感染与亚临床状态ＶＡ缺乏有密切关系。这可能与ＶＡ缺乏所致的呼吸道上皮细胞分化及其完整性受损、免疫功能低下有关。
To investigate the effect of subclinical vitamin A (VA) deficiency on asthma and recurrent respiratory tract infections (RAI) in children, serum VA levels were measured in 22 children with asthma, 27 children with RAI and 35 healthy children by using microfluorescence assay The test. The results showed that children with asthma in all age groups, RAI children with serum VA levels were significantly lower than the normal control group, P <0 05. Children with asthma and recurrent respiratory infections and subclinical VA deficiency are closely related. This may be related to the lack of VA caused by epithelial cell differentiation and damage their integrity, immune dysfunction.