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患者女性,51岁.既往有慢性肾盂肾炎史,近期尿常规及肾功能正常.因高脂血症服非诺贝特(苏卫药准字[87]3560—4号,江苏省溧阳市制药厂生产)0.1,一日三次,服药后血脂下降,2个月后减为0.1,一日二次,至总疗程3个月时出现面部及下肢明显水肿,气促.体格检查;T36.5℃,P72次/分,BP14.7/9.3kpa,发育正常,营养中等,面部及下肢有明显可四性水肿,心肺正常,肝脾未及,左肾区有叩痛.尿常规:蛋白(+),WBC(+),红细胞1～5.血尿素氮7.5mmol/L,肌酐112umol/L.当即停服非诺贝特,改
Patient female, 51 years old with a history of chronic pyelonephritis, recent urinalysis and normal renal function due to hyperlipidemia with fenofibrate (Su Wei Yao Zhun Zi [87] No. 3560-4, Liyang, Jiangsu Province Pharmaceutical Plant production) 0.1, three times a day, decreased blood lipids after medication, reduced to 0.1 after 2 months, twice a day, to the total course of 3 months when the obvious facial and lower limb edema, shortness of breath. Physical examination; T36.5 ℃, P72 / min, BP14.7 / 9.3kpa, normal development, moderate nutrition, facial and lower limbs have obvious four edema, normal heart and lung, liver and spleen are not, the left kidney area has percussion pain. +), WBC (+), red blood cells 1 to 5. Blood urea nitrogen 7.5mmol / L, creatinine 112umol / L. Immediately stop taking fenofibrate, change