PKCε Mediates Substance P Inhibition of GABA_A Receptors-Mediated Current in Rat Dorsal Root Ganglio

• 作 者: 李丽 赵磊 王洋 马克涛 石文艳 王英姿 司军强
• 机 构: DepartmentofPhysiology,KeyLaboratoryofXinjiangEndemicandEthnicDisease,BasicMedicalSchoolofWuhanUnive
• 出 处: Journal of Huazhong University of Science and Technology(Med
• 发表日期: 2015年1期
• 关键词: 背根神经节 激活电流 受体介导 PKC P物质 全细胞膜片钳技术 大鼠 DRG神经元 peripheral nervous system substance P

The mechanism underlying the modulatory effect of substance P(SP) on GABA-activated response in rat dorsal root ganglion(DRG) neurons was investigated. In freshly dissociated rat DRG neurons, whole-cell patch-clamp technique was used to record GABA-activa